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Acne is caused when pores within the skin become blocked, causing inflammation and irritation and the formation of pimples, pustules, or nodules. Sebaceous glands, attached to hair follicles, produce sebum that naturally lubricates the hair and skin. But sometimes, the glands can create too much sebum, which can result in the formation of spots and blemishes, as well as the appearance of oiliness on the skin surface.
Comedonal acne is superficial and mild, presenting in the surface layer of the skin, the epidermis, in the form of white or blackheads. The accumulation of oil, dead skin cells and debris within pores creates a suitable environment for the proliferation of acne-causing bacteria (P.acnes) which triggers the body's immune response. White blood cells then invade the area, forming pimples and pustules, known as whiteheads.
In more severe cases of inflammation and infection, nodules and cysts may develop in the deeper layers of the skin, the dermis. This acne type is much more challenging to treat and can result in scarring and post inflammatory hyperpigmentation in darker skin tones.
Hormones, including testosterone and progesterone, can also play a role in the formation of acne, as they can overstimulate the sebaceous glands, as well as some cosmetic products (comedogenic), medications, smoking and diet.
Blue light is a clinically proven, effective and non-invasive treatment for acne as it stops the proliferation of the P.acnes bacterial cells. Naturally occurring photosensitisers within acne-causing bacteria (P.acnes) absorb the specific wavelength of 415nm blue light, causing cell destruction.
Blue light penetrates the surface layer of the skin, the epidermis (<1 mm) and is beneficial for skin conditions in the epidermal layer.
Blue LED light therapy has an intrinsic microbial effect and is clinically proven to kill acne-causing bacteria (P. acnes) while reducing redness and inflammation, and regulating oil production.
P.acnes bacteria contains naturally occurring photosensitisers, Coproporphyrin III and Protoporphyrin IV. When exposed to a precise wavelength of blue light (415nm), these intercellular porphyrins absorb the light energy, become excited, and produce cytotoxic reactive oxygen species (intercellular free radicals), which kill the bacterial cell.
Blue light 415nm has been clinically proven to kill acne-causing bacteria, P.acnes and is an effective, safe, non-invasive mechanism to treat acne 8 12
Effectively inactivate wound pathogens that can cause infection9
Reduce inflammation 10
Regulate Sebum and oil production 11
Improvement in the treatment of seborrhea (oiliness) 12
Improvement in the treatment of inflammatory acne lesions1 12
Be a viable treatment for psoriasis13